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" ABC transporters and multidrug resistance / "
[edited by] Ahcène Boumendjel, Jean Boutonnat, Jacques Robert.
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BL
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| Record Number
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949432
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b703802
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| Title & Author
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ABC transporters and multidrug resistance /\ [edited by] Ahcène Boumendjel, Jean Boutonnat, Jacques Robert.
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| Publication Statement
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Hoboken, N.J. :: John Wiley & Sons,, ©2009.
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| Page. NO
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1 online resource (xiii, 459 pages) :: illustrations
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| ISBN
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047049512X
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: 9780470495124
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0470227346
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0470495138
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9780470227343
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9780470495131
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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ABC proteins : overview on the description of the structure, the genome, normal tissue expression, physiological aspect, and mechanism of action -- ABC proteins and oncology : expression, detection, and implication of ABC proteins in hematological malignancies and solid tumors -- ABC proteins and pathogenic microorganisms -- MDR modulation through inhibition of ABC transporters : design of inhibitors and mechanism of action -- Biological and clinical aspect of multidrug resistance.
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| Abstract
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Wiley Series in Drug Discovery and Development. Binghe Wang, Series Editor. ABC Transporters and Multidrug Resistance. Edited by. Ahcne Boumendjel. Jean Boutonnat. Jacques Robert. A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance. ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventual.
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ATP-binding cassette transporters.
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Drug resistance in cancer cells.
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Drug Resistance, Multiple.
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Multidrug Resistance-Associated Proteins.
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Neoplasms-- drug therapy.
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ATP-binding cassette transporters.
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Drug resistance in cancer cells.
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SCIENCE-- Life Sciences-- Biochemistry.
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ABC transporters.
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| Dewey Classification
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572/.696
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| LC Classification
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QP552.A87A34 2009
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| NLM classification
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QU 55.7A134 2009
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| Added Entry
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Boumendjel, Ahcène.
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Boutonnat, Jean.
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Robert, Jacques,1949-
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