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BL
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| Record Number
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950313
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b704683
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| Title & Author
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Progress in nucleic acid research and molecular biology.\ edited by Waldo E. Cohn, Kivie Moldave.
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| Publication Statement
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San Diego :: Academic Press,, ©1995.
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| Series Statement
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Progress in nucleic acid research and molecular biology ;; v. 50
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| Page. NO
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1 online resource.
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| ISBN
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0080863388
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: 0125400500
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: 9780080863382
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: 9780125400503
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Cover; Contents; Abbreviations and Symbols; Some Articles Planned for Future Volumes; Chapter 1. Ribosome-catalyzed Peptide-bond Formation; I. The Enzyme; II. The Substrates; III. Reactions with ?UnnaturalŽ Substrates; IV. Implication of 23-S rRNA in Peptide-bond Formation; V. Prospective; References; Chapter 2. Promotion and Regulation of Ribosomal Transcription in Eukaryotes by RNA Polymerase I; I. General Aspects of Ribosomal Gene Regulation; II. Ribosomal Gene Organization and Evolution; III. RNA Polymerase I Promoters; IV. The Basal Transcription Factors
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I. Boundaries and Chromatin Organization of the Human apo-B GeneII. Identification of apo-B Regulatory Elements, Using Cell-Culture Models; III. Probing the in Vivo Function of the apo-B Gene Regulatory Elements; IV. Concluding Remarks; References; Chapter 7. Early Growth Response Protein 1 (Egr-1): Prototype of a Zinc-finger Family of Transcription Factors; I. Overview of Immediate-early Genes; II. Identification of Egr-l cDNA by Differential Screening; III. Egr-l Is Expressed in Response to Diverse Stimuli; IV. Proximal Events; V. Distal Events; VI. In Vivo Role of Egr-1
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IV. Direct Role for Capping Enzyme in Vaccinia Virus TranscriptionV. Yeast mRNA Capping Enzyme; VI. Capping Enzyme from Schizosaccharomyces pombe; VII. Sequence Conservation among Capping Enzymes and Polynucleotide Ligases; VIII. Capping Enzyme and mRNA Identity; IX. Genetic Link between Capping Enzyme and Pre-mKNA Splicing; X. Perspective; References; Chapter 5. Rearrangement of snRNA Structure during Assembly and Function of the Spliceosome; I. General Features of Splicing; II. Dynamic RNA: Technical Considerations; III. RNA-RNA Interactions Early in Spliceosome Assembly
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IV. RNA-RNA Interactions in the Assembling Spliceosome Prior to the First Chemical StepV. Rearrangement of Spliceosomal RNA Structure during the Catalytic Steps of Splicing; VI. Conserved Residues in the Core of the Assembled Spliceosome; VII. Interactions during the Second Catalytic Step; VIII. Modified Nucleotides in Splicing; IX. Release of Spliced mRNA and Regeneration of snRNA Structures; X. Conclusions and Perspectives; References; Chapter 6. Transcriptional Control of the Human Apolipoprotein B Gene in Cell Culture and in Transgenic Animals
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V. Activation at the Ribosomal PromoterVI. Enhancement; VII. Mechanisms of Regulation; VIII. In Conclusion; References; Chapter 3. Targeting and Regulation of Immunoglobulin Gene Somatic Hypermutation and lsotype Switch Recombination; I. Somatic Hypermutation; II. Isotype Switch Recombination; III. Conclusions and Future Directions; References; Chapter 4. Capping Enzyme in Eukaryotic mRNA Synthesis; I. Domain Structure of Vaccinia Virus Capping Enzyme; II. What Is the Rate-limiting Step in Cap Formation?; III. Cotranscriptional Capping of Nascent mRNA
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| Abstract
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FROM THE REVIEWS OF THE PREVIOUS VOLUMES:""In perusing these chapters, I found much of interest. It is worth investigating.""- P. Bricknell in BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY.""Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell.""-BRITISH MEDICAL JOURNAL.* * Provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology* Contributions from leade.
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| Subject
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Molecular biology.
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Nucleic acids.
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Molecular biology.
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Nucleic acids.
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| Dewey Classification
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572.8
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| LC Classification
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QP620.P76eb vol. 50
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| Added Entry
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Cohn, Waldo E.
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Moldave, Kivie,1923-
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