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" Computational toxicology : "


Document Type : BL
Record Number : 950975
Doc. No : b705345
Title & Author : Computational toxicology : : risk assessment for pharmaceutical and environmental chemicals /\ edited by Sean Ekins.
Publication Statement : Hoboken, N.J. :: Wiley-Interscience,, ©2007.
Page. NO : 1 online resource (xxii, 814 pages) :: illustrations (some color)
ISBN : 0470145889
: : 0470145897
: : 9780470145883
: : 9780470145890
: 0470049626
: 9780470049624
Bibliographies/Indexes : Includes bibliographical references and index.
Contents : COMPUTATIONAL TOXICOLOGY; CONTENTS; SERIES INTRODUCTION; PREFACE; ACKNOWLEDGMENTS; CONTRIBUTORS; PART I INTRODUCTION TO TOXICOLOGY METHODS; 1 An Introduction to Toxicology and Its Methodologies; 2 In vitro Toxicology: Bringing the In silico and In vivo Worlds Closer; 3 Physiologically Based Pharmacokinetic and Pharmacodynamic Modeling; 4 Species Differences in Receptor-Mediated Gene Regulation; 5 Toxicogenomics and Systems Toxicology; PART II COMPUTATIONAL METHODS; 6 Toxicoinformatics: An Introduction.
Abstract : In silico modeling for toxicology provides effective pre-screening for chemicals in pharmaceutical discovery and the environment. This work discusses the validation of such models for regulatory purposes, the validation criteria, and other requirements for regulatory acceptance. It also looks at QSAR models, environmental modeling, among others.
Subject : QSAR (Biochemistry)
Subject : Toxicology-- Computer simulation.
Subject : Toxicology-- Mathematical models.
Subject : Computer Simulation.
Subject : Drug-Related Side Effects and Adverse Reactions.
Subject : Environmental Pollutants-- toxicity.
Subject : Risk Assessment.
Subject : Toxicology-- methods.
Subject : Relations structure-activité quantitatives (Biochimie)
Subject : Toxicologie-- Modèles mathématiques.
Subject : Toxicologie-- Simulation par ordinateur.
Subject : MEDICAL-- Toxicology.
Subject : QSAR (Biochemistry)
Subject : Toxicology-- Mathematical models.
Dewey Classification : ‭615.9001/5118‬
LC Classification : ‭RA1199.4.M37‬‭C66 2007eb‬
NLM classification : ‭2007 I-061‬
: ‭QV 602‬‭C738 2007‬
: ‭VT 5300‬rvk
Added Entry : Ekins, Sean.
copyhttps://lib.clisel.com/site/catalogue/950975
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