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" Foye's principles of medicinal chemistry / "
edited by Thomas L. Lemke, David A. Williams ; assistant editors, Victoria F. Roche, S. William Zito [and others].
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BL
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| Record Number
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951837
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b706207
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| Title & Author
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Foye's principles of medicinal chemistry /\ edited by Thomas L. Lemke, David A. Williams ; assistant editors, Victoria F. Roche, S. William Zito [and others].
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| Edition Statement
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6th ed.
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| Publication Statement
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Philadelphia :: Lippincott Williams & Wilkins,, ©2008.
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| Page. NO
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xiv, 1377 pages, 8 pages of plates :: illustrations (some color) ;; 29 cm
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| ISBN
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0781768799
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: 9780781768795
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Historical perspective of medicinal chemistry / John L. Neumeyer -- pt. I: Principles of drug discovery -- Chapter 1: Drug discovery from natural products / A. Douglas Kinghorn -- Chapter 2: Drug design and relationship of functional groups to pharmacologic activity / James J. Knittel and Robin M. Zavod -- Chapter 3: Molecular modeling and in Silico drug design / Xiang-Qun (Sean) Xie -- Chapter 4: Receptors and drug action / Timothy A. Maher and David A. Johnson -- Chapter 5: Drug discovery through enzyme inhibition / Stephen Kerr -- Chapter 6: Pharmaceutical biotechnology-from nucleic acids to personalized medicine / Ronald E. Reid and Robert D. Sindelar -- Chapter 7: Peptide and protein drugs / Michael Mokotoff -- Chapter 8: Antisense therapeutic agents / Marilyn Speedie -- Chapter 9: Physicochemical and biopharmaceutical properties of drug substances and pharmacokinetics / Sunil S. Jambhekar -- Chapter 10: Drug metabolism / David A. Williams -- Chapter 11: U.S. drug regulation: an overview / Douglas -- Part II: Drug receptors affecting neurotransmission and enzymes as catalytic receptors : overview of Drug Receptors: A Perspective / David J. Triggle -- Chapter 12: Drugs affecting cholinergic neurotransmission / E. Kim Fifer -- Chapter 13: Adrenergic receptors and drugs affecting adrenergic neurotransmission / Robert K. Griffith -- Chapter 14: Serotonin receptors and drugs affecting serotonergic neurotransmission / Richard A. Glennon and Malgorzata Dukat-Glennon -- Chapter 15: Amino acid neurotransmitters in the central nervous system / Timothy J. Maher -- Chapter 16: Inhibitors of nerve conduction: local anesthetics / Matthias C. Lu -- Chapter 17: Phosphodiesterase inhibitors / Kevin Dalby -- Part III: Pharmacodynamic Agents -- Section 1: Drugs affecting central nervous system -- Chapter 18: General anesthetics / Timothy J. Maher -- Chapter 19: Sedative-hypnotics / William Soine -- Chapter 20: Antiseizure agents / Barbara Leduc -- Chapter 21: Antidepressants / David A. Williams -- Chapter 22: Psychotherapeutic drugs: antipsychotic and anxiolytic agents / Raymond G. Booth -- Chapter 23: Hallucinogens, stimulants and related drugs of abuse / Richard A. Glennon -- Chapter 24: Opioid analgesics / David S. Fries -- Chapter 25: Drugs used to treat neuromuscular disorders: antiparkinsonian and spasmolytic agents / Raymond G. Booth.
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Section 2: Drugs affecting the cardiovascular system -- Chapter 26: Cardiac agents: Cardiac glycosides, antianginal, and antiarrhythmic drugs / Ahmed S. Mehanna -- Chapter 27: Diuretics / Gary O. Rankin -- Chapter 28: Angiotensin converting enzyme inhibitors, antagonists and calcium blockers / Marc Harrold -- Chapter 29: Central and peripheral sympatholytics and vasodilators / David A. Williams -- Chapter 30: Antihyperlipoproteinemics and inhibitors of cholesterol biosynthesis / Marc Harrold -- Chapter 31: Antithrombotics, thrombolytics, coagulants, and plasma extenders / Matthias C. Lu and Thomas L. Lemke -- Section 3: Drugs affecting the hormonal systems -- Chapter 32: Insulin and drugs used for the treatment of diabetes / Robin M. Zavod, John L. Krstenansky, and Bruce L. Currie -- Chapter 33: Adrenocorticoids / Duane D. Miller, Robert W. Brueggemeier and James T. Dalton -- Chapter 34: Thyroid function and thyroid drugs / Ali R. Banijamali -- Chapter 35: Calcium homeostasis / Robin M. Zavod -- Section 4: Drugs affecting the immune systems -- Chapter 36: Nonsteroidal anti-inflammatory drugs / Wendel L. Nelson -- Chapter 37: Antihistamines and related antiallergic and antiulcer agents -- Section 5: Chemotherapeutic agents -- Chapter 38: Antibiotics and antimicrobial agents / Lester A. Mitscher, Thomas L. Lemke, and Elmer J. Gentry -- Chapter 39: Antiparasitic agents: Thomas L. Lemke -- Chapter 40: Antifungal agents / Robert K. Griffith -- Chapter 41: Antimycobacterial agents /Thomas L. Lemke -- Chapter 42: Cancer and chemotherapy / Victoria F. Roche -- Chapter 43: Antiviral agents and protease inhibitors / Patrick M. Woster -- Part IV: Disease state management -- Chapter 44: Asthma and chronic obstructive pulmonary disease S. William Zito -- Chapter 45: Men' Health / Duane D. Miller, Robert W. Brueggermeier, and James T. Dalton -- Chapter 46: Women's Health / Robin M. Zavod.
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| Abstract
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This comprehensive text has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. Emphasis is on patient-focused pharmaceutical care and on the pharmacist as a therapeutic consultant, rather than a chemist. A new disease state management section explains appropriate therapeutic options for asthma, chronic obstructive pulmonary disease, and men's and women's health problems. Also new to this edition: Clinical Significance boxes, Drug Lists at the beginning of appropriate chapters, and an eight-page color insert with detailed illustrations of drug structures. Clinical Significance boxes show students how the content in each of the chapters relates to effective pharmaceutical care. Drug Lists at the beginning of appropriate chapters are bulleted lists that provide students with a summary of the drugs covered within the chapter.
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| Subject
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Pharmaceutical chemistry.
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Chimie pharmaceutique.
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Pharmaceutical chemistry.
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Pharmakologie
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Pharmazeutische Chemie
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Pharmakologie.
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Pharmazeutische Chemie.
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| Subject
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Chemistry, Pharmaceutical.
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| Dewey Classification
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616.07/56
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| LC Classification
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RS403.P75 2008
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| NLM classification
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2007 L-720
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QV 744F7962 2008
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44.33bcl
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VS 5010rvk
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XI 1800rvk
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| Added Entry
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Foye, William O.
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Lemke, Thomas L.
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Williams, David A.,1938-
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| Parallel Title
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Principles of medicinal chemistry
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