| Document Type
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BL
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| Record Number
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955381
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| Doc. No
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b709751
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| Title & Author
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Structural biology of membrane proteins /\ edited by Reinhard Grisshammer and Susan K. Buchanan.
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| Publication Statement
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Cambridge, UK :: Royal Society of Chemistry,, ©2006.
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| Series Statement
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RSC biomolecular sciences
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| Page. NO
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1 online resource (xxiii, 392 pages) :: illustrations (some color)
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| ISBN
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1847552560
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: 9781847552563
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9780854043613
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Refolding of G-protein-coupled receptors -- Expression of genes encoding eukaryotic membrane proteins in mammalian cells -- Expression of recombinant G-protein coupled receptors for structural biology -- The purification of G-protein coupled receptors for crystallization -- An introduction to detergents and their use in membrane protein studies -- Solution NMR approaches to the structure and dynamics of integral membrane proteins -- Membrane proteins studied by solid-state NMR -- Assessing structure and dynamics of native membrane proteins -- State-of-the-art methods in electron microscopy, including single-particle analysis -- Atomic resolution structures of integral membrane proteins using cubic lipid phase crystallization -- Aquaporins : integral membrane channel proteins -- Gas channels for ammonia -- Channels in the outer membrane of mycobacter -- The structure of the SecY protein translocation channel -- Structure and function of the translocator domain of bacterial autotransporters -- X-Ray crystallographic structures of sarcoplasmic reticulum Ca2+-ATPase at the atomic level -- Comparison of the multidrug transporter EmrE structures determined by electron cryomicroscopy and X-ray crystallography -- Structure of photosystems I and II -- Glutamate receptor ion channels : structural insights into molecular mechanisms -- The mitochondrial ADP/ATP carrier.
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| Abstract
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In the last few years there have been many exciting and innovative developments in the field of membrane protein structure and this trend is set to continue. Structural Biology of Membrane Proteins is a new monograph covering a wide range of topics with contributions from leading experts in the field. The book is split into three sections: the first discusses topics such as expression, purification and crystallisation; the second covers characterisation techniques and the final section looks at new protein structures. The book will hence have wide appeal to researchers working in and around the field and provide an up-to-date reference source. Introductory sections to each topic are accompanied by more detailed discussions for the more experienced biochemist. Detailed descriptions of experimental methods are included to demonstrate practical approaches to membrane protein structure projects. The book also offers an up-to-date reference source in addition to descriptions of new and emerging developments, including state-of-the-art techniques for solving membrane protein structures. Structural Biology of Membrane Proteins encompasses both basic introductions and detailed descriptions of themes and should appeal to a wide range of biochemical scientists, both experienced and beginner.
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| Subject
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Membrane proteins.
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Amino Acids, Peptides, and Proteins
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Analytical, Diagnostic and Therapeutic Techniques and Equipment
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Biochemical Phenomena.
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Chemical Phenomena.
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Chemicals and Drugs
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Chemistry Techniques, Analytical.
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Crystallization.
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Investigative Techniques
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Membrane Proteins.
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Molecular Structure.
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Phenomena and Processes
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Proteins.
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Chemistry.
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Membrane proteins.
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SCIENCE-- Life Sciences-- Biochemistry.
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Science.
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| Dewey Classification
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572.696
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| LC Classification
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QP552.M44S77 2006eb
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| Added Entry
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Buchanan, Susan K.
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Grisshammer, R. K., (Reinhard K.)
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