|
" Immunoinformatics : "
edited by Darren R. Flower.
Document Type
|
:
|
BL
|
Record Number
|
:
|
958960
|
Doc. No
|
:
|
b713330
|
Title & Author
|
:
|
Immunoinformatics : : predicting immunogenicity in silico /\ edited by Darren R. Flower.
|
Publication Statement
|
:
|
Totowa, N.J. :: Humana,, ©2007.
|
Series Statement
|
:
|
Methods in molecular biology ;; 409
|
Page. NO
|
:
|
1 online resource (xv, 438 pages) :: illustrations (some color)
|
ISBN
|
:
|
1280945257
|
|
:
|
: 160327118X
|
|
:
|
: 661094525X
|
|
:
|
: 9781280945250
|
|
:
|
: 9781603271189
|
|
:
|
: 9786610945252
|
|
:
|
1588296997
|
|
:
|
9781588296993
|
Bibliographies/Indexes
|
:
|
Includes bibliographical references and index.
|
Contents
|
:
|
Immunoinformatics and the in silico prediction of immunogenicity. An introduction / D.R. Flower -- IMGT, the international immunogenetics information system for immunoinformatics. Methods for querying IMGT databases, tools, and web resources in the context of immunoinformatics / M.P. Lefranc -- The IMGT/HLA database / J. Robinson and S.G. Marsh -- IPD: The immuno polymorphism database / J. Robinson and S.G. Marsh -- SYFPEITHI: Database for searching and T-cell epitope prediction / M.M. Schuler, M.D. Nastke and S. Stevanovikc -- Searching and mapping of T-cell epitopes, MHC binders, and tap binders / M. Bhasin, S. Lata and G.P. Raghava -- Searching and mapping of B-cell epitopes in bcipep database / S. Saha and G.P. Raghava -- Searching haptens, carrier proteins, and anti-hapten antibodies / S. Srivastava [and others] -- The classification of HLA supertypes by grid/cpca and hierarchical clustering methods / P. Guan, I.A. Doytchinova and D.R. Flower -- Structural basis for HLA-A2 supertypes / P. Kangueane and M.K. Sakharkar -- Definition of MHC supertypes through clustering of MHC peptide-binding repertoires / P.A. Reche and E.L. Reinherz -- Grouping of class I HLA alleles using electrostatic distribution maps of the peptide binding grooves / P. Kangueane and M.K. Sakharkar -- Prediction of peptide-MHC binding using profiles / P.A. Reche and E.L. Reinherz -- Application of machine learning techniques in predicting MHC binders / S. Lata, M. Bhasin and G.P. Raghava -- Artificial intelligence methods for predicting T-cell epitopes / Y. Zhao, M.H. Sung and R. Simon -- Toward the prediction of class I and II mouse major histocompatibility complex-peptide-binding affinity: In silico bioinformatic step-by-step guide using quantitative structure-activity relationships / C.K. Hattotuwagama, I.A. Doytchinova and D.R. Flower -- Predicting the MHC-peptide affinity using some interactive-type molecular descriptors and QSAR models / T.H. Lin -- Implementing the modular MHC model for predicting peptide binding / D.S. DeLuca and R. Blasczyk -- Support vector machine-based prediction of MHC-binding peptides / P. Donnes -- In silico prediction of peptide-MHC binding affinity using SVRMHC / W. Liu [and others] -- HLA-peptide binding prediction using structural and modeling principles / P. Kangueane and M.K. Sakharkar -- A practical guide to structure-based prediction of MHC-binding peptides / S. Ranganathan and J.C. Tong -- Static energy analysis of MHC class I and class II peptide-binding affinity / M.N. Davies and D.R. Flower -- Molecular dynamics simulations: Bring biomolecular structures alive on a computer / S. Wan, P.V. Coveney and D.R. Flower -- An iterative approach to class II predictions / R.R. Mallios -- Building a meta-predictor for MHC class II-binding peptides / L. Huang [and others] -- Nonlinear predictive modeling of MHC class II-peptide binding using bayesian neural networks / D.A. Winkler and F.R. Burden -- TAPPred prediction of TAP-binding peptides in antigens / M. Bhasin, S. Lata and G.P. Raghava -- Prediction methods for B-cell epitopes / S. Saha and G.P. Raghava -- Histocheck. Evaluating structural and functional MHC similarities / D.S. DeLuca and R. Blasczyk -- Predicting virulence factors of immunological interest / S. Saha and G.P. Raghava -- Immunoinformatics. Predicting immunogenicity in silico. Preface / D.R. Flower.
|
Abstract
|
:
|
Immunoinformatics: Predicting Immunogenicity In Silico is a primer for researchers interested in this emerging and exciting technology and provides examples in the major areas within the field of immunoinformatics. This volume both engages the reader and provides a sound foundation for the use of immunoinformatics techniques in immunology and vaccinology. The volume is conveniently divided into four sections. The first section, Databases, details various immunoinformatic databases, including IMGT/HLA, IPD, and SYEPEITHI. In the second section, Defining HLA Supertypes, authors discuss supertypes of GRID/CPCA and hierarchical clustering methods, Hla-Ad supertypes, MHC supertypes, and Class I Hla Alleles. The third section, Predicting Peptide-MCH Binding, includes discussions of MCH binders, T-Cell epitopes, Class I and II Mouse Major Histocompatibility, and HLA-peptide binding. Within the fourth section, Predicting Other Properties of Immune Systems, investigators outline TAP binding, B-cell epitopes, MHC similarities, and predicting virulence factors of immunological interest. Immunoinformatics: Predicting Immunogenicity In Silico merges skill sets of the lab-based and the computer-based science professional into one easy-to-use, insightful volume.
|
Subject
|
:
|
Immunoinformatics.
|
Subject
|
:
|
Immunological tolerance-- Computer simulation.
|
Subject
|
:
|
Immunology-- Computer simulation.
|
Subject
|
:
|
Allergy and Immunology.
|
Subject
|
:
|
Analytical, Diagnostic and Therapeutic Techniques and Equipment
|
Subject
|
:
|
Anatomy.
|
Subject
|
:
|
Biological Science Disciplines.
|
Subject
|
:
|
Biology.
|
Subject
|
:
|
Computational Biology-- methods.
|
Subject
|
:
|
Computational Biology.
|
Subject
|
:
|
Databases as Topic.
|
Subject
|
:
|
Databases, Factual.
|
Subject
|
:
|
Disciplines and Occupations
|
Subject
|
:
|
Genetics.
|
Subject
|
:
|
Health Occupations.
|
Subject
|
:
|
Hemic and Immune Systems
|
Subject
|
:
|
Immune System.
|
Subject
|
:
|
Immunogenetics.
|
Subject
|
:
|
Informatics.
|
Subject
|
:
|
Information Science.
|
Subject
|
:
|
Information Storage and Retrieval.
|
Subject
|
:
|
Investigative Techniques
|
Subject
|
:
|
Medical Informatics.
|
Subject
|
:
|
Medicine.
|
Subject
|
:
|
Methods.
|
Subject
|
:
|
Models, Biological.
|
Subject
|
:
|
Models, Immunological.
|
Subject
|
:
|
Models, Theoretical.
|
Subject
|
:
|
Natural Science Disciplines.
|
Subject
|
:
|
Immunoinformatics.
|
Subject
|
:
|
Immunology-- Computer simulation.
|
Subject
|
:
|
SCIENCE-- Life Sciences-- Anatomy Physiology.
|
Subject
|
:
|
Allergy and Immunology.
|
Subject
|
:
|
Computational Biology-- methods.
|
Subject
|
:
|
Databases, Factual.
|
Subject
|
:
|
Immunogenetics-- methods.
|
Subject
|
:
|
Immunoinformatics.
|
Subject
|
:
|
Immunological tolerance-- Computer simulation.
|
Subject
|
:
|
Immunology-- Computer simulation.
|
Subject
|
:
|
Medical Informatics-- methods.
|
Dewey Classification
|
:
|
571.960285
|
LC Classification
|
:
|
QR182.2.I46I463 2007
|
NLM classification
|
:
|
QW 504I3247 2007
|
|
:
|
W1ME9616J v.409 2007
|
|
:
|
R392clc
|
Added Entry
|
:
|
Flower, Darren R.
|
| |