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" Glucokinase and glycemic disease : "
volume editors, F.M. Matschinsky, M.A. Magnuson.
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BL
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| Record Number
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965973
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b720343
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| Title & Author
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Glucokinase and glycemic disease : : from basics to novel therapeutics /\ volume editors, F.M. Matschinsky, M.A. Magnuson.
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| Publication Statement
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Basel ;New York :: Karger,, 2004.
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| Series Statement
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Frontiers in diabetes,; v. 16
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1 online resource (ix, 406 pages) :: illustrations.
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| ISBN
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1417564911
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: 3318010804
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: 9781417564910
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: 9783318010800
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3805577443
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9783805577441
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| Bibliographies/Indexes
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Includes bibliographical references and indexes.
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| Contents
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Preface / Matschinsky, F.M.; Magnuson, M.A. -- Chapter 1. Background -- Glucokinase as a Glucose Sensor : Past, Present and Future / Magnuson, M.A.; Matschinsky, F.M. -- The Hexokinase Gene Family / Wilson, J.E. -- Comparative Biochemistry of Glucokinase / Cardenas, M.L. -- Chapter 2. Human Biomedical Studies -- Maturity Onset Diabetes of the Young Type 2 / Velho, G. [and others] -- Permanent Neonatal Diabetes mellitus due to Glucokinase Deficiency / Njolstad, P.R. [and others] -- Glucokinase-Linked Hypoglycemia : Clinical Aspects of Activating Glucokinase Mutations / Christesen, H.B.T. [and others] -- Glucokinase and the Regulation of Blood Sugar : A Mathematical Model Predicts the Threshold for Glucose Stimulated Insulin Release for GCK Gene Mutations that Cause Hyper- and Hypoglycemia / Gloyn, A.L. [and others] -- Glucokinase/Glutamate Dehydrogenase Interactions in the GDH form of Congenital Hyperinsulinism / Kelley, A.; Li, C.; Stanley, C.A. -- Chapter 3. Structure and Function -- Glucokinase : A Monomeric Enzyme with Positive Cooperativity / Cornish-Bowden, A.; Cardenas, M.L. -- Molecular Models of Human Glucokinase and the Implications for Glycemic Diseases / Harrison, R.W.; Weber, I.T. -- Crystal Structure of Human Liver Glucokinase Bound to a Small Molecule Allosteric Activator : Insights into the Activating Mutations / Dunten, P. [and others] -- Chapter 4. Regulation of Glucokinase -- Molecular Biology of Glucokinase Regulation / Iynedjian, P.B. -- Role of the Transcription Factor Sterol Regulatory Element Binding Protein-1c in Hepatic Glucokinase Gene Regulation / Foufelle, F.; Ferre, P. -- Regulation of Hepatic Glucokinase Gene Expression / Postic, C.; Decaux, J.-F.; Girard, J. -- Discovery and Role of Glucokinase Regulatory Protein / van Schaftingen, E.; Veiga da Cunha, M. -- GKRP/GK: Control of Metabolic Fluxes in Hepatocytes / Agius, L. [and others] -- Regulation of Glucokinase as Islets Adapt to Pregnancy / Sorenson, R.L.; Weinhaus, A.J.; Brelje, T.C. -- Regulation of Glucokinase by Vitamins and Hormones / Fernandez-Mejia, C.; German, M.S. -- Regulation of [beta]-Cell GK Gene Transcription by Insulin / Leibiger, B.; Berggren, P.-O.; Leibiger, I.B. -- Interaction of GK with the Bifunctional Enzyme 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (6PF2K/F26P2ase) / Baltrusch, S. [and others] -- Role of Sulfhydril Groups in GK Catalysis for GK Function / Tiedge, M.; Baltrusch, S.; Lenzen, S. (Hannover) -- Chapter 5. Tissue-Specific Functions -- Mouse Models of Altered Glucokinase Gene Expression / Magnuson, M.A.; Kim, K.-A. -- Anatomy, Physiology and Regulation of Glucokinase as a Brain Glucosensor / Levin, B.E. [and others] -- A Glucokinase/AP-1 Glucose Transduction Mechanism in the Ventromedial Hypothalamic Satiety Center / Yang, X.-j. [and others] -- The Hepatoportal Glucose Sensor : Mechanisms of Glucose Sensing and Signal Transduction / Thorens, B. -- Linear Relationship between Glucokinase Expression, Metabolic Redox State and Insulin Secretion / Piston, D.W.; Patterson, G.H. -- Glucokinase in [beta]-Cell Insulin-Secretory Granules / Miwa, I.; Toyoda, Y.; Yoshie, S.-- Chapter 6: Glucokinase as Drug Target -- Discovery and Actions of Glucokinase Activators / Grimsby, J.; Matschinsky, F.M.; Grippo, J.F. -- Balancing Hepatic Glucose Disposal and Production : Key Regulatory Genes and Therapeutic Opportunities / Yang, R.; Newgard, C.B.
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| Subject
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Diabetes.
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Glucokinase.
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Diabète.
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Glucose-- Métabolisme.
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Hexokinase.
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Diabetes mellitus-- Pharmakotherapie, Aufsatzsammlung.
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Diabetes.
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Glucokinase-- Physiologie, Aufsatzsammlung.
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Glucokinase.
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HEALTH FITNESS-- Diseases-- Diabetes.
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Pharmakotherapie-- Diabetes mellitus, Aufsatzsammlung.
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Glucose Metabolism Disorders-- metabolism.
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Glucose Metabolism Disorders-- therapy.
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Glucokinase-- metabolism.
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Glucokinase-- secretion.
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Glucokinase-- therapeutic use.
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Models, Molecular.
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| Dewey Classification
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616.462
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| LC Classification
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QP606.G57G59 2004eb
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| NLM classification
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W1FR945X v.16 2004
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WD 200.5.G6G567 2004
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| Added Entry
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Magnuson, M. A., (Mark A.)
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Matschinsky, F. M., (Franz M.)
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