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" Advances in genetics. "
edited by Jeffrey C. Hall, Jay C. Dunlap, Theodore Friedmann, Francesco Giannelli.
Document Type
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BL
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Record Number
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970223
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Doc. No
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b724593
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Title & Author
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Advances in genetics.\ edited by Jeffrey C. Hall, Jay C. Dunlap, Theodore Friedmann, Francesco Giannelli.
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Publication Statement
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New York, N.Y. :: Academic Press,, 1998.
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Series Statement
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Advances in genetics ;; 38
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Page. NO
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1 online resource (vii, 225 pages) :: illustrations, diagrams.
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ISBN
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0080568254
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: 0120176386
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: 1281725013
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: 6611725016
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: 9780080568256
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: 9780120176380
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: 9781281725011
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: 9786611725013
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Bibliographies/Indexes
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Includes bibliographical references and index.
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Contents
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Front Cover; Advances in Genetics, Volume 38; Copyright Page; Contents; Contributors; Chapter 1. Body Plan Genes and Human Malformation; I. Introduction; II. Establishing the Body Axes; III. Patterning the Limb; IV. Patterning the Ocular Anlage; V. Patterning the Tooth Anlage; References; Chapter 2. Molecular Genetics of the Hereditary Ataxias; I. Introduction; II. The Autosomal Dominant Progressive Ataxias; III. Friedreich Ataxia; References; Chapter 3. The Minute Genes in Drosophila and Their Molecular Functions; I. Introduction; II. Historical Review.
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III. Minutes as Genetic Tools in Studies of Growth and DevelopmentIV. Minutes and the Protein Synthesis Theory; V. Conclusions and Prospects; References; Chapter 4. Genetics of Biological Rhythms in Drosophila; I. Introduction; II. Chronogenetics; III. Chronogenetic Biology; IV. A Final Chronogenetic Thought; References; Chapter 5. DNA Breakage and Repair; I. Introduction; II. Formation of DNA Strand Breaks; III. Mechanisms for the Repair of DNA DSBs; IV. Identification of Genes Required for NHEJ; V. Characterization of Proteins Involved in NHEJ by Biochemical, Molecular, and Genetic Analysis.
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VI. DNA-PK as a Protein KinaseVII. The Mechanism of NHEJ; VIII. The Contribution of NHEJ and HR to DSB Rejoining in Yeast versus Mammalian Cells; IX. DNA-PK-Defective Mice; X. Radiosensitivity and Immune Deficiency; XI. A Model for NHEJ; XII. Summary; References; Index.
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Abstract
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This volume of Advances in Genetics furthers the serial's goal of presenting topics of interest to both human and molecular geneticists. Topics of interest in this volume include: Expression patterns of regulatory genes and the role they play in development Hereditary ataxias and specific disease states where the genetic defect has been identified Minute genes, their mutations, and their molecular function in Drosophila The genetics and molecular biology of rhythm mutants and clock molecules Double strand breaks in DNA and their repair mechanisms Key Features * Expression patterns of regulatory genes and the role they play in development * Hereditary ataxias and specific disease states where the genetic defect has been identified * Minute genes, their mutations, and their molecular function in Drosophila * The genetics and molecular biology of rhythm mutants and clock molecules * Double-strand breaks in DNA and their repair mechanisms and lack of repair mechanisms resulting in human disorders.
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Subject
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Genetics.
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Subject
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Human genetics.
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Subject
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Genetics.
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Subject
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Human genetics.
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Subject
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SCIENCE-- Life Sciences-- Genetics Genomics.
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Dewey Classification
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576.5
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LC Classification
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QH431.A1A3838 1998eb
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Added Entry
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Dunlap, Jay C.
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Friedmann, Theodore,1935-
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Giannelli, Francesco.
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Hall, Jeffrey C.
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