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BL
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| Record Number
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971047
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b725417
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| Title & Author
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Advances in cancer research.\ edited by George F. Vande Woude, George Klein.
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| Publication Statement
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San Diego, Calif. :: Academic Press,, ©2001.
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| Series Statement
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Advances in cancer research ;; v. 80
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| Page. NO
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1 online resource.
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| ISBN
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0080524389
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: 0120066807
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: 9780080524382
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: 9780120066803
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| Notes
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Title from PDF title page (viewed Sep. 27, 2007).
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Front Cover; Advances in Cancer Research; Copyright Page; Contents; Contributors to Volume 80; Chapter 1. Involvement of Platelet-Derived Growth Factor in Disease: Development of Specific Antagonists; I. Introduction; II. Platelet-Derived Growth Factor (PDGF) and PDGF Receptors; III. Intracellular Signal Transduction; IV. In Vivo Function of Pdgf; V. Pdgf in Disease; VI. Pdgf and Pdgf Receptors as Drug Targets; VII. Future Perspectives; References; Chapter 2. Tumor Suppression Activity of Adenovirus E1a Protein: Anoikis and the Epithelial Phenotype; I. Introduction
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II. Hereditary Colorectal Cancer SyndromesIII. Tumor Mutations and Molecular Clocks: Gateways to the Fourth Dimension; References; Chapter 5. Primary Effusion Lymphoma: A Liquid Phase Lymphoma of Fluid-Filled Body Cavities; I. Definition of Primary Effusion Lymphoma; II. Histogenes of Primary Effusion Lymphoma; III. Pathogenesis of Primary Effusion Lymphoma; IV. Epidemiology of Primary Effusion Lymphoma; V. Clinical Features of Primary Effusion Lymphoma; VI. Radioimaging of Primary Effusion Lymphoma; VII. Differential Diagnosis of Primary Effusion Lymphoma
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II. Historical Development of E1a as a Tumor SuppressorIII. Epithelial Conversion: Phenomenology; IV. Epithelial Conversion: Mechanisms; V. Anoikis Sensitization and Tumor Suppression by E1a; References; Chapter 3. Comparative Analysis of the Transforming Mechanisms of Epstein-Barr Virus, Kaposi's Sarcoma-Associated Herpesvirus, and Herpesvirus Saimiri; I. Introduction; II. Comparative Analysis of Gamma Herpesvirus Gene Products; III. Conclusion; References; Chapter 4. Genetic Predisposition and Somatic Diversification in Tumor Development and Progression; I. Introduction
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IV. The Top1 Catalytic Cycle and Cleavage ComplexesV. Anticancer Top1 Poisons; VI. Suppression and/or Enhancement of Top1 Cleavage Complexes by DNA Damage; VII. Processing of Top1-Mediated Dna Lesions; VIII. Conclusions; References; Index
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VIII. Therapy of Primary Effusion LymphomaIX. Perspectives; References; Chapter 6. Dimensions of Antigen Recognition and Levels of Immunological Specificity; I. Introduction; II. Logical Preliminaries: Boundaries of Categories and Categories of Boundaries; III. Monovalent Recognition; IV. Multivalent Recognition; V. Specificity of Cellular Activation; VI. Organismal Specificity; VII. Conclusions; References; Chapter 7. Topoisomerase I-Mediated DNA Damage; I. Introduction; II. Structural Domains of Top1; III. Top1 Functions and Protein Interactions
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| Abstract
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Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here once again, outstanding and original reviews are presented on a variety of topics including platelet-derived growth factor in disease, genetic predisposition in tumor development, primary effusion lymphoma, and many more. Key Features* Involvement of Platelet-Derived Growth Factor in Disease: Development of Specific Antagonists* Tumor Suppression Activity of Adenovirus E1a Protein: Anoikis and the Epithelial Phenotype* Comparative Analysis of the Transforming Mechanisms of.
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| Subject
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Cancer-- Research.
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Cancer-- Research.
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HEALTH FITNESS-- Diseases-- Cancer.
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| Subject
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MEDICAL-- Oncology.
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| Dewey Classification
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616.99/40072
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| LC Classification
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RC267.A38eb vol. 80
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| Added Entry
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Klein, George,1928-1981.
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Vande Woude, George F.
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