| Document Type
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BL
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| Record Number
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971593
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b725963
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| Title & Author
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Advances in immunology.\ edited by Frank J. Dixon.
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| Publication Statement
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San Diego :: Academic Press,, 1990.
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| Series Statement
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Advances in Immunology ;; v. 48
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| Page. NO
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1 online resource (vii, 380 pages) :: illustrations
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| ISBN
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0080578241
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: 0120224488
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: 1281727458
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: 9780080578248
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: 9780120224487
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: 9781281727459
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Front Cover; Advances in Immunology, Volume 48; Copyright Page; Contents; Chapter 1. Internal Movements in Immunoglobulin Molecules; I. Introduction; II. Methods for the Study of Ig Flexibility; III. Segmental Flexibility of Ig Molecules; IV. Internal Motions in Fab and Fc Subunits; V. Role of the Hinge Region Structure for Segmental Flexibility; VI. Functional Implications of Segmental Flexibility; VII. Evolution of Ig Flexibility; VIII. Mobility of Carbohydrate Components; IX. Conclusions; References; Chapter 2. Somatic Diversification of the Chicken Immunoglobulin light-Chain Gene.
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I. IntroductionII. Bursa of Fabricius Is Essential for Normal B Cell Development; III. Structure of the Unique Chicken IgL Gene; IV. Rearrangement of the IgL, Gene; V. Early Role of the Bursa: Selection if Ig+ Precursors; VI. Bursal Stem Cell; VII. Developing Bursal Lymphocytes Acquire Diversity within the Rearranged IgL Gene Segment; VIII. Sequences That Lead to Diversification of the Rearranged VL Gene Segment Have Identical Counterparts in the fV Gene Segments Located 5' of VL.; IX. Diversification Results in a Cell in Which the VL Gene Segment Has Undergone Conversion.
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II. Corneal Allografts: Immunogenically Privileged Grafts on Immunologically Privileged Graft BedsIII. Immunological Privilege of the Anterior Chamber; IV. Effect of Immune Regulation on Intraocular Tumor Rejection; V. Immune Regulation and Autoimmune Uveitis; VI. Uveitis: A Breakdown in Self-Tolerance and Immune Privilege; VII. Is Cataract Formation an Immune-Mediated Disease?; VIII. Conclusions; References; Chapter 7. Molecular Events Mediating T Cell Activation; I. Introduction; II. T Cell Surface Activation Molecules; III. PI Turnover and Formation of Second Messengers in T Cells.
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II. HLA Class II Structures: Genes and MoleculesIII. HLA Class II Polymorphism and Typing; IV. HLA Class II Hybrid (Intra- or Interisotypic) Molecules; V. Diseases; VI. Concluding Remarks and Perspectives; References; Chapter 5. Neuroimmunology; I. Introduction; II. T Cell Components of Autoimmune Reactions to the Nervous System; III. Production and Functional Effects of Cytokines and Other Mediators of Neuroimmunological Reactions; IV. Lymphocyte Receptors for Neuromediators; V. Conclusions; References; Chapter 6. Immune Privilege and Immune Regulation in the Eye; I. Introduction.
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X. Somatic Diversification of the Ig VL Gene Repertoire by Gene Conversion Is a General Feature of Avian Ig GenesXI. Additional Mechanisms of Ig Diversification; XII. Summary; References; Chapter 3. T Lymphocyte-Derived Colony-Stimulating Factors; I. Introduction; II. Colony-Stimulating Factors; III. T Lymphocyte Production of CSFs in Vitro; IV. Inducibility and Regulation of CSF Synthesis; V.T Lymphocyte Heterogeneity; VI. CSF Production of T Lymphocytes in Vivo; References; Chapter 4. The Molecular Basis of Human Leukocyte Antigen Class II Disease Associations; I. Introduction.
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| Abstract
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ADVANCES IN IMMUNOLOGY VOLUME 48.
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| Subject
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Allergy.
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Immunology.
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Allergy.
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Immunology.
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MEDICAL-- Immunology.
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| Dewey Classification
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616.07/9
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| LC Classification
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QR180.A248 1990eb
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