| Document Type
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BL
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| Record Number
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972909
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| Doc. No
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b727279
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| Title & Author
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Multiple sclerosis therapeutics /\ edited by Jeffrey A. Cohen, Richard A. Rudick ; prefaces written by Henry McFarland.
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| Edition Statement
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2nd ed.
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| Publication Statement
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London ;New York :: Martin Dunitz,, 2003.
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| Page. NO
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1 online resource (xxiii, 754 pages) :: illustrations
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| ISBN
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0203639111
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: 1135414025
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: 1135414068
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: 1135414076
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: 9780203639115
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: 9781135414023
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: 9781135414061
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: 9781135414078
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1841842265
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9781841842264
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| Notes
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Previous edition: 1999.
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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""Book Cover""; ""Half-Title""; ""Title""; ""Copyright""; ""Contents""; ""Contributors""; ""Preface to First Edition""; ""Preface to Second Edition""; ""Acknowledgements""; ""I Introduction""; ""1 Aspects of multiple sclerosis that relate to clinical trial design and treatment ""; ""II Clinical trial methodology""; ""2 Measures of neurologic impairment and disability in multiple sclerosis""; ""3 Assessment of neuropsychological function in multiple sclerosis""; ""4 Health-related quality of life assessment in multiple sclerosis""
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""13 Ethical considerations in multiple sclerosis clinical trials""""14 The process of drug development and approval in the USA, the European Union, and Canada""; ""15 Sponsors, monitoring committees and investigators: the investigator�s perspective""; ""16 Guidelines for clinical trials of new therapeutic agents in multiple sclerosis: reporting extended results from phase III clinical trials""; ""17 The failed clinical trial in multiple sclerosis""
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""18 The challenge of long-term studies in multiple sclerosis: use of pooled data, historical controls, and observational studies to determine efficacy""""19 Emerging concepts of pathogenesis: relationship to therapies for multiple sclerosis""; ""III Clinical trials of disease-modifying therapy""; ""33 Complementary and alternative treatments in multiple sclerosis""; ""32 Sex hormones and other pregnancy-related factors with therapeutic potential in multiple sclerosis""; ""31 Combination therapies in multiple sclerosis""; ""30 Emerging disease-modifying therapies for multiple sclerosis""
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""29 Treatment of multiple sclerosis by hematopoietic stem cell transplantation""""28 Cyclophosphamide treatment of multiple sclerosis""; ""27 Treatment of multiple sclerosis with methylprednisolone""; ""26 Therapeutic plasma exchange for multiple sclerosis""; ""25 Intravenous immunoglobulin to treat multiple sclerosis""; ""24 Use of mitoxantrone to treat multiple sclerosis""; ""23 Glatiramer acetate as therapy for multiple sclerosis""; ""22 Biological responses to type I interferons: relationship to therapeutic effects in multiple sclerosis""
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""5 Magnetic resonance imaging in multiple sclerosis: an overview""""6 Measures of gadolinium enhancement in multiple sclerosis ""; ""7 Measures of magnetization transfer in multiple sclerosis""; ""8 Measures of T1 and T2 relaxation in multiple sclerosis""; ""9 Measurement of central nervous system atrophy""; ""10 Measures to quantify axonal damage in vivo based on magnetic resonance spectroscopy in multiple sclerosis""; ""11 Functional imaging in multiple sclerosis""; ""12 Use of cost analyses to improve understanding of the therapeutic trade-offs for multiple sclerosis""
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| Subject
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Multiple sclerosis-- Treatment.
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Multiple sclerosis.
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HEALTH FITNESS-- Diseases-- Alzheimer's Dementia.
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MEDICAL-- Neurology.
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Multiple sclerosis-- Treatment.
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| Subject
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Multiple sclerosis.
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Multiple Sclerosis-- therapy.
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Clinical Trials-- methods
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Magnetic Resonance Imaging.
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Multiple Sclerosis-- pathology.
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| Subject
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Outcome Assessment, Health Care.
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| Dewey Classification
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616.83406
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| LC Classification
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RC377.M85 2003eb
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| NLM classification
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2003 C-127
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WL 360M9596 2003
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| Added Entry
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Cohen, Jeffrey A., (Jeffrey Alan),1954-
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Rudick, Richard A.
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