| Document Type
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BL
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| Record Number
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973562
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| Doc. No
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b727932
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| Title & Author
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Advances in clinical chemistry /\ edited by Gregory S. Makowski.
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| Publication Statement
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New York :: Academic Press,, 2005.
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| Series Statement
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Advances in clinical chemistry ;; 39
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| Page. NO
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1 online resource (xv, 301 pages) :: illustrations, diagrams.
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| ISBN
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0080458297
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: 0120103397
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: 1280633085
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: 1281004634
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: 6610633088
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: 9780080458298
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: 9780120103393
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: 9781280633089
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: 9781281004635
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: 9786610633081
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0080458297
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| Contents
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Front Cover -- Advances in Clinical Chemistry -- Copyright Page -- Contents -- Contributors -- Preface -- Chapter 1. Clinical and Analytical Review of Ischemia-Modified Albumin Measured by the Albumin Cobalt Binding Test -- 1. Introduction -- 2. IMA and the ACB Test -- 3. Clinical Studies Review -- 4. Future Needs and Unanswered Questions -- 5. Summary -- References -- Chapter 2. Human Tissue Kallikreins: From Gene Structure to Function and Clinical Applications -- 1. Introduction.
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10. Hormonal Regulation of Kallikreins -- 11. Evolution of Kallikreins -- 12. Cross-Talk Between Kallikreins: A Possible Novel Enzymatic Cascade Pathway -- 13. Isoforms and Splice Variants of the Human Kallikreins -- 14. Kallikreins in Normal Physiology -- 15. Association of Kallikreins with Human Diseases -- 16. Kallikreins and Cancer -- 17. Therapeutic Applications -- 18. Future Directions -- References -- Chapter 3. Cholesterol and Lipids in Depression: Stress, Hypothalamo-Pituitary-Adrenocortical Axis, and Inflammation/Immunity -- 1. Introduction.
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2. Discovery of the Human Tissue Kallikrein Gene Locus: A Short Historical Perspective -- 3. Kallikreins in Rodents and Other Species -- 4. Characterization and Sequence Analysis of the Human Tissue Kallikrein Gene Locus -- 5. Structural Features of the Human Tissue Kallikrein Genes and Proteins -- 6. Sequence Variations of Human Kallikrein Genes -- 7. The Tissue Kallikreins in the Context of Other Serine Proteases in the Human Genome -- 8. Tissue Expression and Cellular Localization of the Kallikrein Genes -- 9. Regulation of Kallikrein Activity.
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2. The Relationships Between Lipid Profile Levels, Depression, and Suicide Attempts -- 3. The Interactions Between Stress, Lipid Profiles, Cortisone/HPA Axis, and Inflammation/Immunity -- 4. Clinical Phenotypes in Depression and Molecular Levels -- 5. Conclusion -- References -- Chapter 4. Advances on Biological Markers in Early Diagnosis of Alzheimer Disease -- 1. Introduction -- 2. Biological Aspects of AD Pathogenesis -- 3. Diagnostic Issues -- 4. Biological Markers and Early Diagnosis of AD -- 5. CSF Biomarkers -- 6. Peripheral Biomarkers.
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7. Future Approaches in Preclinical Diagnosis of AD -- 8. Conclusive Remarks -- References -- Chapter 5. Endothelial Microparticles (EMP) as Vascular Disease Markers -- 1. Introduction -- 2. Characterization of EMPs -- 3. Methodology to Detect EMP -- 4. EMPs in Clinical Disease -- 5. Perspective -- References -- Chapter 6. Proteomics in Clinical Laboratory Diagnosis -- 1. Introduction to Proteomics -- 2. Modern Proteomic Technology -- 3. Proteins, Proteomics, and Patterns -- 4. Accessing Biological Samples.
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| Abstract
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Volume thirty-nine in the internationally acclaimed Advances in Clinical Chemistry, contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical exploration to cutting edge microarray technology. In keeping with the tradition of the series, this volume emphasizes novel laboratory advances with application not only to both clinical laboratory diagnostics, but as well as practical basic science studies. This volume of Advances in Clinical Chemistry is an indispensable resource and practical guide for twenty-first century practitioners of clinical chemistry, molecular diagnostics, pathology, and clinical laboratory sciences in general. *Presents advances in assay methods such as immuno-PCR technology and proteomic assessment *Discusses the development and potential applications of novel biomarkers of chronic conditions (i.e, . Alzheimer's disease, cancer, cardiovascular disease and depression) *Addresses molecular and biochemical findings in the aging process.
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| Subject
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Biochemistry.
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| Subject
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Clinical chemistry.
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| Subject
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Biochemistry.
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| Subject
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Clinical chemistry.
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| Dewey Classification
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616.075
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| LC Classification
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RB1.A2 2005eb
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| Added Entry
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Makowski, Gregory S.
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