| Document Type
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BL
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| Record Number
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974148
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b728518
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| Title & Author
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Advances in cancer research.\ edited by George Klein, Sidney Weinhouse.
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| Publication Statement
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New York :: Academic Press,, 1982.
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| Series Statement
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Advances in cancer research ;; v. 37
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| Page. NO
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1 online resource (ix, 402 pages) :: illustrations.
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| ISBN
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0080562191
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: 0120066378
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: 6611738622
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: 9780080562193
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: 9780120066377
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: 9786611738624
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Front Cover; Advances in Cancer Research, Volume 37; Copyright Page; Contents; Contributors to Volume 37; Chapter 1. Retroviruses and Cancer Genes; I. Introduction; II. Introducing Retrovirus Oncogenes; III. Properties of Retrovirus Oncogenes and Their Products; IV. The Origin of Retrovirus Oncogenes: Emergence of the Thesis; V. The Discovery of c-oncs; VI. Characterizing c-oncs; VII. C-oncs Are Cellular Genes; VIII. The Expression of c-oncs; IX. Proteins Encoded by C-oncs; X. How Similar Are Viral Oncogenes and c-oncs?; XI. Are c-oncs Members of a Multigene Family?
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Chapter 4. Pericellular Matrix in Malignant TransformationI. Introduction; II. Components of the Extracellular Matrix and Their Functions; III. Pericellular Matrix and the Cellular Phenotype in Vitro; IV. Malignant Transformation: Altered Biosynthesis of Matrix Components and Failure to Deposit Them; V. Tumorigenicity Invasion and Metastasis; VI. Proteins of Basement Membranes and Interstitial Matrix as Characteristics of Tumor Cells; VII. Cell-Matrix Interaction and Anchorage Dependence of Normal Cells
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IV. Description of the Drosophila Tumor MutantsV. Viruses Found in Drosophila Tumor Cells; VI. Retroviral Oncogenes and Their Cellular Counterparts in Different Animal Species; VII. Transfection and Vertebrate Tumor Genes: A Comparison with Drosophila; VIII. Concluding Remarks; References; Chapter 3. Transformation-Associated Tumor Antigens; I. Introduction; II. Simian Virus 40; III. Adenoviruses; IV. Epstein-Barr Virus; V. Methylcholanthrene-Induced Transformed Cells (Meth A); VI. Abelson Virus; VII. Rous Sarcoma Virus; VIII. Teratocarcinomas; IX. Conclusions; References
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VIII. Molecular Mechanisms of Altered Cell-Matrix Interaction in Rous Sarcoma Virus TransformationReferences; Chapter 5. Radiation Oncogenesis in Cell Culture; I. Foreword; II. Introduction; III. Cell Transformation in Vitro; IV. Radiation Oncogenesis in Vitro; V. Discussion; References; Chapter 6. Mhc Restriction and Ir Genes; I. Mhc through a Keyhole; II. How Was Mhc Restriction Discovered?; III. Mhc Restriction of Cytolytic Responses; IV. Mhc Restriction of Regulatory Responses; V. Mhc Restriction of DTH and CS Responses; VI. The Puzzle of the Class I and Class II Gene Dichotomy
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XII. How Might Retroviruses Transduce Cellular Genes?XIII. What Is the Function of c-oncs in Normal Cells?; XIV. The Paradox of Neoplastic Transformation by Retrovirus Oncogenes; XV. Does the Homology between Viral Oncogenes and c-oncs Dictate the Host Range of Viral Transformation?; XVI. Do c-oncs Provide a Pathway for Oncogenesis?; XVII. Conclusion: The Pursuit of Cancer Genes; References; Chapter 2. Cancer, Genes, and Development: The Drosophila Case; I. Introduction; II. Drosophila Development; III. General Information on the Drosophila Tumor Mutants
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| Abstract
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ADVANCES IN CANCER RESEARCH, VOLUME 37.
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| Subject
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Cancer-- Research.
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Carcinogenesis.
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Cancer-- Research.
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Carcinogenesis.
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HEALTH FITNESS-- Diseases-- Cancer.
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MEDICAL-- Oncology.
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| Dewey Classification
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616.99/40072
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| LC Classification
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RC267.A4537 1982eb
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| Added Entry
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Klein, George,1925-2016.
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Weinhouse, Sidney,1909-
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