| Document Type
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BL
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| Record Number
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974657
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b729027
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| Title & Author
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Advances in cancer research.\ edited by George Vande Woude.
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| Publication Statement
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New York :: Academic Press,, 1992.
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| Series Statement
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Advances in cancer research ;; v. 60
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| Page. NO
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1 online resource (312 pages) :: illustrations.
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| ISBN
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0080562426
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: 0120066602
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: 1281409251
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: 6611409254
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: 9780080562421
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: 9780120066605
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: 9781281409256
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: 9786611409258
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Front Cover; Advances in Cancer Research, Volume 60; Copyright Page; Contents; Contributors; Chapter 1. Structural and Functional Diversity in the FGF Receptor Multigene Family; I. Introduction; II. The FGF Family of Polypeptide Mitogens; III. Early Binding and Cross-Linking Studies of the FGF Receptor; IV. Nomenclature of the FGF Receptor Genes; V. Purification, cDNA Cloning, and Characterization of FGFR 1; VI. Characterization of EFGR 2, FGFR 3, and FGFR 4; VII. Multiple Forms of FGFR 1 and FGFR 2 Are Generated by Alternative Splicing; VIII. Multiple Forms of FGFR 1
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I. The Multidrug Transporter as a Cause of Multidrug ResistanceII. Regulation of Expression of mdr Genes; III. Summary and Conclusions; Reference; Chapter 6. Relationship between MYC Oncogene Activation and MHC Class I Expression; I. Introduction; II. MHC Class I Expression and Cancer; III. Modulation of MHC Class I Expression by Oncogences; IV. Molecular Mechanism of MHC Class I Regulation by Oncogenes; V. Biological Consequences of MHC Class I Downmodulation by Oncogenes; VI. Concluding Remarks; References; Chapter 7. Immunosuppressive Factors in Human Cancer; I. Introduction
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IX. Multiple Forms of FGFR 2X. FGFR 3 and FGFR 4; XI. Ligand Binding Specificities of the Cloned FGF Receptors; XII. Alternative Splicing in the Third Ig Domain Is Important for Determining Ligand Binding Specificities; XIII. Analogous Splice Variants from Different FGF Receptor Genes Encode Receptor Forms with Different Ligand Binding Specificities; XIV. Regulation of FGF Receptor Expression; XV. Cell- and Tissue-Specific Alternative Splicing of FGF Receptor mRNAs; XVI. Differential, Tissue-Specific Expression of the Different ' FGF Receptor Genes; XVII. The Drosophila FGF Receptor
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V. Chromosomal AbnormalitiesVI. Tumor Suppressor Genes; VII. Gene Amplification; VIII. Predictors of Tumor Behavior; IX. Molecular Cloning of Translocation Breakpoints; X. Future Developments; Reference; Note Added in Proof; Chapter 4. Genomic instability and Tumor Progression: Mechanistic Considerations; I. Introduction; II. Genomic Stability and Instability: Background and Implications; III. Mechanisms of Genomic Stability and Instability; IV. Quantitative Considerations; V. Summary and Perspectives; References; Chapter 5. Function and Regulation of the Human Multidrug Resistance Gene
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XVIII. FGF Receptor-Mediated Signal TransductionXIX. Concluding Remarks; References; Chapter 2. Protein Tyrosine Kinase Growth Factor Receptors and Their Ligands in Development, Differentiation, and Cancer; I. Introduction; II. Structure of Receptor Protein Tyrosine Kinases; III. RTKs in Development; IV. RTKs and Tumorigenesis; V. Genetics and Cancer; Reference; Chapter 3. The Molecular and Genetic Characterization of Human Soft Tissue Tumors; I. Introduction; II. Tumor Etiology; III. Genetic Susceptibility to Soft Tissue Tumors; IV. Detection of ras Gene Activation
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| Abstract
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ADVANCES IN CANCER RESEARCH, VOLUME 60.
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| Subject
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Cancer-- Research.
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Oncology, Experimental.
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Cancer-- Research.
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HEALTH FITNESS-- Diseases-- Cancer.
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MEDICAL-- Oncology.
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| Subject
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Oncology, Experimental.
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| Dewey Classification
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616.9940072
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| LC Classification
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RC267.A4560 1992eb
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| Added Entry
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Vande Woude, George F.
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