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BL
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| Record Number
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975508
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b729878
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| Title & Author
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Advances in immunology.\ edited by Frank J. Dixon ; associate editors, Frederick Alt [and others].
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| Publication Statement
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San Diego [Calif.] :: Academic Press,, ©2001.
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| Series Statement
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Advances in immunology ;; 79
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| Page. NO
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1 online resource (x, 343 pages) :: illustrations.
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| ISBN
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0080493645
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: 0120224798
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: 1281010502
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: 6611010505
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: 9780080493640
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: 9780120224791
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: 9781281010506
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: 9786611010508
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Front Cover; Advances in Immunology; Copyright Page; Contents; Contributors; Chapter 1. Neutralizing Antiviral Antibody Responses; I. Introduction; II. Antiviral Antibody Responses; III. Mechanisms of Neutralization by Antibodies; IV. The Role of Complement, Natural Antibodies, and Fc-Receptors in Antiviral Responses; V. The Role of Antigen Structure, Organization, and Dose on B Cell Responses; VI. T-Cell Dependent Activation of B Cells in Viral Infections; VII. B Cell Unresponsiveness; VIII. Examples of Nonclassical Virus Neutralization; IX. Virus Escape from Neutralizing Antibody Responses
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II. Recognition of Foreign MoleculesIII. Serine Protease Cascades and Thioester-Containing Proteins; IV. Induction and Regulation of the Antimicrobial Genes; V. Concluding Remarks; References; Chapter 6. Functional Heavy-Chain Antibodies in Camelidae; I. Introduction; II. Natural Occurrence of Heavy-Chain Antibodies in Camelidae; III. Adaptations in the H Chain; IV. The L Chains; V. Heavy-Chain Antibody Generation; VI. Isolation of Antigen-Specific Heavy-Chain Antibodies, or VHHs; VII. VHH Structure and VHH-Antigen Interaction; VIII. Biotechnological Importance of VHHs; References
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III. Interactions Mediated by LAT, SLP-76, and BLNK and Their Role in Antigen Receptor SignalingIV. Mechanisms of Signaling by LAT and SLP-76; References; Chapter 4. Xenotransplantation; I. Introduction; II. The Need; III. History of Clinical Xenotransplantation; IV. Choice of Species; V. Mechanisms of Xenograft Rejection; VI. Therapeutic Approaches; VII. Nonimmunologic Barriers to Xenotransplantation; VIII. Future of Xenotransplantation; References; Chapter 5. Regulation of Antibacterial and Antifungal Innate Immunity in Fruitflies and Humans; I. Introduction
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X. Immunological MemoryXI. Neutralizing Antibodies and Vaccine Strategies; XII. Conclusions; References; Chapter 2. Regulation of Interleukin-12 Production in Antigen-Presenting Cells; I. Introduction; II. The Discovery of IL-12; III. Molecular Structure of IL-12; IV. Biological Functions of IL-12; V. Receptors of IL-12 and Signaling; VI. Producer Cells of IL-12; VII. Pathways of IL-12 Induction; VIII. Molecular Regulation of the Expression of IL-12 Genes; IX. Cytokine-Mediated Regulation of IL-12 Production; X. Role of Cell-Surface Receptors in the Regulation of IL-12 Production
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XI. Endotoxin-Tolerance-Mediated Inhibition of IL-12XII. Inhibition of IL-12 Production by Anti-in.ammatory Hormones and Small Molecules; XIII. Looking to the Future; References; Chapter 3. Mechanisms of Signaling by the Hematopoietic-Specific Adaptor Proteins, SLP-76 and LAT and Their B Cell Counterpart, BLNK/SLP-65; I. The Role of Adaptors in Signaling by ITAM-Coupled Receptors: An Overview; II. Genetic Models Reveal the Essential Roles of SLP-76, LAT, and BLNK in ITAM-Coupled Signaling Pathways
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| Abstract
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Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
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| Subject
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Immunology.
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| Subject
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Immunology.
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| Subject
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MEDICAL-- Pharmacology.
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| Dewey Classification
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615/.37
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| LC Classification
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QR181.A38eb vol. 79
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| Added Entry
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Alt, Frederick W.
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Dixon, Frank J., (Frank James),1920-2008.
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