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BL
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| Record Number
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975657
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b730027
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| Title & Author
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Advances in clinical chemistry.\ edited by Gregory S. Makowski ; associate regional editors, Gerard Nowacki, Kwang-Jen Hsiao.
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| Publication Statement
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Amsterdam ;Boston :: Elsevier/Academic Press,, ©2004.
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| Series Statement
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Advances in clinical chemistry ;; v. 38
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| Page. NO
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1 online resource.
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| ISBN
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0080490271
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: 0120103389
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: 9780080490274
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: 9780120103386
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| Notes
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Title from PDF title page (viewed July 18, 2007).
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Front Cover; Advances in CLINICAL CHEMISTRY; Copyright Page; CONTENTS; Contributors; Preface; Chapter 1. Lipoprotein Oxidation Products and Arteriosclerosis: Theory and Methods with Applicability to the Clinical Chemistry Laboratory; 1. Introduction; 2. Radicals, Electrophiles, and Other Reactive Species.; 3. Oxidation Products of Lipids and Proteins and Measurement Methods; 4. Detailed Procedures for Some Methods that Measure Oxidation Products in Plasma; 5. Discussion; 6. Conclusion; References
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5. Prophylaxis6. Treatment; 7. Future Trends; 8. Summary; References; Chapter 7. The Potential of Protein-Detecting Microarrays for Clinical Diagnostics; 1. Introduction; 2. Diagnostic Signatures; 3. Protein-Detecting Microarrays; 4. Conclusions; References; Chapter 8. Clinical Laboratory Implications of Single Living Cell mRNA Analysis; 1. Introduction; 2. AFM; 3. Manipulations of Biological Material with AFM; 4. mRNA Extraction from Living Cells; 5. Modification of AFM Tips; References; Letter to the Editor; Index; Color Plate Section
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Chapter 2. Measurement of Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of Metalloproteinases (TIMP) in Blood and Urine: Potential Clinical Applications1. Introduction; 2. Background; 3. Biology and Chemistry of MMPs and TIMPs; 4. Involvement of MMPs and TIMPs in Pathophysiology of Disease; 5. Assays for Measurement of MMPs and TIMPs in Body Fluids; 6. Blood Levels of MMPs and TIMPs in Physiologic and Disease States (Table 2); 7. Miscellaneous Diseases Associated with Increased Levels of MMPs and TIMPs; 8. MMPs Identified in Urine of Patients with Cancer; 9. Conclusions; References
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Chapter 3. Molecular Method to Quantitatively Detect Micrometastases and its Clinical Significance in Gastrointestinal Malignancies1. Introduction; 2. Methodology; 3. Quantitative Detection of Micrometastases and its Prognostic Significance; 4. General Considerations and Future Directions; References; Chapter 4. Zymographic Evaluation of Plasminogen Activators and Plasminogen Activator Inhibitors; 1. Introduction; 2. Monitoring the PA/PAI System; 3. Materials and Methods for Overlay Zymography; 4. Results; 5. Conclusion; References
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Chapter 5. Estrogen Metabolites, Conjugates, and DNA Adducts: Possible Biomarkers for Risk of Breast, Prostate, and Other Human Cancers1. Introduction; 2. Analysis of Estrogens and their Metabolites, Conjugates, and Depurinating DNA Adducts; 3. Biomarkers for Increased Risk of Developing Estrogen-Initiated Cancer; References; Chapter 6. Organophosphates/Nerve Agent Poisoning: Mechanism of Action, Diagnosis, Prophylaxis, and Treatment; 1. Introduction; 2. Chemistry, Mechanism of Action, and Symptoms; 3. Cholinesterase Inhibitors and Other Factors Influencing the Activity; 4. Diagnosis
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| Abstract
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Volume thirty-eight in the series of the internationally acclaimed Advances in Clinical Chemistry, contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical exploration to cutting edge microarray technology. In keeping with the tradition of the series, this volume emphasizes novel laboratory advances with application not only to both clinical laboratory diagnostics, but as well as practical basic science studies. This volume of Advances in Clin.
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| Subject
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Clinical chemistry.
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| Subject
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Clinical chemistry.
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MEDICAL-- Clinical Medicine.
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| Subject
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SCIENCE-- Chemistry-- Clinical.
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| Dewey Classification
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616.07/56
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| LC Classification
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RB40.A38eb vol. 38
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| NLM classification
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W1AD54
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| Added Entry
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Hsiao, Kwang-Jen.
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Makowski, Gregory S.
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Nowacki, Gerard.
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