| Document Type
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BL
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| Record Number
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976652
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| Doc. No
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b731022
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| Title & Author
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Allosteric receptor modulation in drug targeting /\ edited by Norman G. Bowery.
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| Publication Statement
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New York :: Taylor & Francis,, 2006.
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| Page. NO
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1 online resource (xii, 359 pages, 1 unnumbered leaf of plates) :: illustrations (some color)
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| ISBN
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0824727916
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: 1280863412
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: 1420016180
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: 6610863415
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: 9780824727918
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: 9781280863417
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: 9781420016185
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: 9786610863419
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Sect. I. Basic principles. Allosteric modulation of receptor function / Stephen Daniels -- Characteristics of allosterism in drug action / Terry P. Kenakin -- Predicting dose-response curve behavior / David A. Hall -- Sect. II. Ionotropic receptors. Allosteric modulation of GABAa receptors / Hanns Möhler -- Allosteric interactions at the NMDA receptor channel complex / Manolo Mugnaini -- 5-HT3 receptors / Li Zhang and Sarah C.R. Lummis -- Nicotinic receptors / R.C. Hogg and D. Bertrand -- Sect. III. G-protein-coupled receptors. Allosteric modulation of G-protein-coupled receptors / Willem Soudijn, Ineke van Wijngaarden, and Ad P. Ijzerman -- Allosteric modulators of group III metabotropic glutamate receptors as novel therapeutics / Jesper Mosolff Mathiesen and M. Teresa Ramirez -- Allosteric modulation of GABAb receptors / Stephan Urwyler -- Allosteric interactions at GABAb and related G-protein-coupled receptors / David I.B. Kerr and Jennifer Ong -- Muscarinic receptors / Christian Tränkle -- [alpha]2-Adrenoceptors / Emma S.J. Robinson and Alan L. Hudson.
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| Abstract
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Offering illustrations and tables in every chapter, this book extensively covers the principles of allosterism in reference to drug action and progresses to a detailed examination of individual ionotropic and G-protein coupled receptor systems. It helps those new to the subject understand the importance of allosterism.
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| Subject
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Allosteric regulation.
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Drug targeting.
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| Subject
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Allosteric regulation.
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| Subject
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Drug targeting.
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MEDICAL-- Pharmacology.
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Allosteric Regulation.
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| Subject
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Drug Delivery Systems.
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| Subject
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Receptors, G-Protein-Coupled.
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| Subject
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Receptors, Neurotransmitter.
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| Dewey Classification
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615/.7
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| LC Classification
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QP517.A55A55 2006eb
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| NLM classification
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2006 J-359
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QU 34A441 2006
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| Added Entry
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Bowery, N. G.
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