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" Chiral separations by liquid chromatography : "
Satinder Ahuja, editor.
Document Type
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BL
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Record Number
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982428
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Doc. No
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b736798
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Title & Author
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Chiral separations by liquid chromatography : : developed from a symposium sponsored by the Division of Analytical Chemistry at the 200th national meeting of the American Chemical Society, Washington, D.C., August 26-31, 1990 /\ Satinder Ahuja, editor.
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Publication Statement
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Washington, DC :: American Chemical Society,, 1991.
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Series Statement
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ACS symposium series ;; 471
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Page. NO
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x, 239 pages :: illustrations ;; 24 cm.
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ISBN
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0841221162
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: 9780841221161
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Bibliographies/Indexes
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Includes bibliographical references and index.
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Contents
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Chiral separations : an overview / Satinder Ahuja -- Analytical criteria for chiral high-pressure liquid chromatography / Thomas D. Doyle -- Commercially available brush-type chiral selectors for the direct resolution of enantiomers / S.R. Perrin and W.H. Pirkle -- Chiral separations using native and functionalized cyclodextrin-bonded stationary phases in high-pressure liquid chromatography / Randy A. Menges and Daniel W. Armstrong -- Chromatographic optical resolution on polysaccharide carbamate phases / Yoshio Okamoto, Yuriko Kaida, Ryo Aburatani, and Koichi Hatada -- Protein column-based chiral reversed-phase liquid chromatography / S.G. Allenmark -- Optimization of chiral separations on silica-bonded [alpha]1-acid glycoprotein by mobile phase additives / E. Arvidsson, S.O. Jansson, and G. Schill -- Chiral recognition on biopolymer-based high-pressure liquid chromatographic chiral stationary phases : a case for multiple interaction sites / Irving W. Wainer, Terence A.G. Noctor, Enrico Domenici, and Philippe Jadaud -- Chiral separations and modes of association of hydrogen-bonding molecules / E. Gil-Av -- Liquid chromatographic separation of enantiomers by hydrogen-bond association / Akira Dobashi, Yasuo Dobashi, and Shoji Hara -- High-pressure liquid chromatographic resolution of optical isomers / Influence of mobile and [pi]-donor chiral stationary phases / Subhash C. Dhanesar -- Direct stereochemical high-pressure liquid chromatographic separation of aminoglutethimide and its major metabolite : its applications to biological fluids / Hassan Y. Aboul-Enein and M. Rafiqul Islam -- Amino acid racemization : a tool for dating? / Veronika R. Meyer.
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Abstract
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"A definitive reference for researchers working on problems involving chirality. Presenting state-of-the-art information, this volume covers all the major modes of separation and offers contributions from the leading researchers who developed these techniques. Four chapters provide a detailed review of the commonly used columns: brush type, cyclodextrin, polysaccaride carbonate, and protein. Many of the papers focus on HPLC, a technique which is also ideally suited for large scale preparation of optical isomers. In addition, the volume provides significant discussion on the use of chiral discriminators or selectors."--Publisher description (LoC).
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Subject
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Enantiomers-- Separation, Congresses.
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Subject
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Liquid chromatography, Congresses.
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Subject
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Chromatographie en phase liquide, Congrès.
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Subject
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Énantiomères-- Séparation, Congrès.
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Subject
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Chiralité.
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Subject
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Chromatographie en phase liquide-- Congrès.
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Subject
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Énantiomères-- Séparation-- Congrès.
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Subject
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Enantiomers-- Separation.
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Subject
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Liquid chromatography.
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Subject
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Structure-Activity Relationship.
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Subject
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Chromatography, Liquid-- methods.
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Subject
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Drug Design.
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Dewey Classification
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543/.0894
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LC Classification
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QD79.C454C475 1991
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NLM classification
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35.29bcl
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Added Entry
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Ahuja, Satinder,1933-
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Added Entry
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American Chemical Society., Division of Analytical Chemistry.
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American Chemical Society., Meeting(200th :1990 :, Washington, D.C.)
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