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" Emerging cancer therapy : "
edited by Arsénio M. Fialho and Ananda M. Chakrabarty.
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BL
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| Record Number
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988177
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| Doc. No
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b742547
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| Title & Author
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Emerging cancer therapy : : microbial approaches and biotechnological tools /\ edited by Arsénio M. Fialho and Ananda M. Chakrabarty.
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| Publication Statement
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Hoboken, N.J. :: Wiley,, ©2010.
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| Page. NO
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1 online resource (xiii, 432 pages) :: illustrations
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| ISBN
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0470444673
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: 0470626518
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: 0470626526
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: 9780470444672
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: 9780470626511
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: 9780470626528
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Salmonella typhimurium mutants selected to grow only in tumors to eradicate them in nude mouse models / Robert M. Hoffman -- The use of living Listeria monocytogenes as an active immunotherapy for the treatment of cancer / John Rothman [and others] -- Bacillus Calmete-Guerin (BCG) for urothelial carcinoma of the bladder / Timothy P. Kresowik and Thomas S. Griffith -- Live clostridia : a powerful tool in tumor biotherapy / Lieve Van Mellaert, Ming Q. Wei, and Jozef Ann -- Bifidobacterium as a delivery system of functional genes for cancer gene therapy / Geng-Feng Fu [and others] -- Replication-selective viruses for the treatment of cancer / Padma Sampath and Steve H. Thorne -- Engineering Herpes simplex virus for cancer oncolytic virotherapy / Jason S. Buhrman, Tooba A. Cheema, and Giulia Fulci -- Promiscuous anticancer drugs from pathogenic bacteria : rational versus intelligent drug design / Arsenio M. Fialho and Ananda M. Chakrabarty -- Arginine Deiminase and cancer therapy / L. Feun [and others] -- Cytosine deaminase/5-fluorocytosine molecular cancer chemotherapy / Sergey A. Kaliberov and Donald J. Buchsbaum -- Bacterial proteins against metastasis / A.M.E. Walenkamp -- Pseudomonas exotoxin A-based immunotoxins for targeted cancer therapy / Philipp Wolf and Ursula Elsesser-Beile -- Denileukin Diftitox in novel cancer therapy / Lin-Chi Chen and Nam H. Dang -- The application of cationic antimicrobial peptides in cancer treatment : laboratory investigations and clinical potential / Ashley Hilchie and David W. Hoskin -- Prodiginines and their potential utility as proapoptotic anticancer agents / Neil R. Williamson [and others] -- Farnesyltransferase inhibitors of microbial origins in cancer therapy / Jingxuan Pan and Sai-Ching Jim Yeung -- The use of RNA and CpG dna as nucleic acid-based therapeutics / Jorg Vollmer -- The role and importance of intellectual property generation and protection in drug development / Arsenio M. Fialho and Ananda M. Chakrabarty.
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| Abstract
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Explores current and emerging applications of microbes as cancer-fighting agents. Today, treatment options for cancer patients typically include surgery, radiation therapy, immunotherapy, and chemotherapy. While these therapies have saved lives and reduced pain and suffering, cancer still takes millions of lives every year around the world. In recent years, researchers have been working on a new strategy: developing microbes and microbial products that specifically attack cancer cells. This book breaks new ground in emerging cancer treatment modalities by presenting recent advances in the use of microorganisms and viruses as well as their products in cancer therapy. Seventeen chapters review the application of live microorganisms, high and low molecular weight products derived from microorganisms, and microbial products fused to cancer-targeting molecules. In addition, the book highlights the benefits of a multi-target approach to destroy cancer cells. --From publisher's description.
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| Subject
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Bacteria-- Therapeutic use.
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Cancer-- Treatment.
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Microbial biotechnology.
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Viruses-- Therapeutic use.
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Antineoplastic Agents.
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Bacteria-- immunology.
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Biotechnology.
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Neoplasms-- therapy.
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Cancer-- Treatment.
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HEALTH FITNESS-- Diseases-- Cancer.
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MEDICAL-- Oncology.
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Microbial biotechnology.
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Viruses-- Therapeutic use.
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| Dewey Classification
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616.99/406
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| LC Classification
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RC271.V567E64 2010eb
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| NLM classification
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2010 J-073
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QZ 266E53 2010
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| Added Entry
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Chakrabarty, Ananda M.,1938-
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Fialho, Arsenio.
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