| Document Type
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BL
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| Record Number
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993005
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| Doc. No
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b747375
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| Title & Author
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The hereditary basis of rheumatic diseases /\ Rikard Holmdahl, editor.
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| Publication Statement
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Basel ;Boston :: Birkhäuser,, ©2006.
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| Series Statement
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Progress in inflammation research
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| Page. NO
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1 online resource (ix, 178 pages) :: illustrations
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| ISBN
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1280625996
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: 376437201X
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: 3764374195
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: 6610625999
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: 9781280625992
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: 9783764372019
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: 9783764374198
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: 9786610625994
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Cover -- Contents -- List of contributors -- A. Introduction -- Genetics of joint inflammation -- problems and possibilities -- B. Genetic studies on rheumatic diseases -- The epidemiology of rheumatoid arthritis and the use of linkage and association studies to identify disease genes -- Heterogeneity in rheumatoid arthritis based on expression analysis: towards personalised medicine -- Gene-based large scale LD-mapping of rheumatoid arthritis-associated genes -- C. Shared heredity of rheumatic diseases -- Emerging relationships: rheumatoid arthritis and the PTPN22 associated autoimmune disorders -- Shared genes in rheumatic diseases, the role of PD1 and the RUNX genes in disease susceptibility -- The role of B27 and other genes associated with ankylosing spondylitis -- D. Tools for analysing complexity -- Emerging tools for dissecting complex disease -- Expression analysis of rheumatic diseases, prospects and problems -- The use of humanized MHC mouse strains for studies of rheumatic diseases -- SKG mice, a monogenic model of autoimmune arthritis due to altered signal transduction in T-cells -- A genetic approach to select and validate new targets for treatment of rheumatic diseases -- Index -- Last Page.
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| Abstract
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Deals with the genetic basis and regulation of rheumatic diseases. The first part of this book describes genetic studies on rheumatic diseases. The second part deals with the shared heredity of rheumatic diseases, and the third part describes tools for analysing complexity. It is intended for researchers and clinicians from rheumatology.
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| Subject
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Rheumatism-- Genetic aspects.
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| Subject
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MEDICAL-- Rheumatology.
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| Subject
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Rheumatism-- Genetic aspects.
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| Subject
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Rheumatic Diseases-- genetics.
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| Subject
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Rheumatism-- Genetic aspects.
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| Subject
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Arthritis, Rheumatoid-- genetics.
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| Subject
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Rheumatic Diseases-- genetics.
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| Dewey Classification
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616.7/23042
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| LC Classification
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RC927.H47 2006
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| NLM classification
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2006 L-010
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WE 544H542 2006
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R593. 21clc
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| Added Entry
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Holmdahl, Rikard,1953-
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